Genipin

Genipin the aglycon of geniposide found in gardenia fruit has long been considered for treatment of inflammatory diseases in traditional oriental medicine Genipin has recently been reported to have some pharmacological functions such as antimicrobial antitumor and anti-inflammatory effects

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Genipin

Genipin No : N2408 CAS No : 6902-77-8 Formula: C11H14O5 M Wt: 226 23 Synonyms: Target: Natural Products Pathway: Storage: Store at -20C In Vitro ≥9 8 mg/mL in DMSO ≥101 6 mg/mL in EtOH ≥5 97 mg/mL in H2O Preparing Stock Solutions Mass Solvent 1mg 5mg 10mg Concentration 1 mM 4 4203 mL 22 1014 mL 44 2028 mL

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SAFETY DATA SHEET Page: 1 of 5 Genipin Revision

Genipin SAFETY DATA SHEET Supersedes Revision: 01/16/2015 according to Regulation (EC) No 1907/2006 as amended by (EC) No 2015/830 and US OSHA HCS 2015 1 1 Product Code: 10010622 Section 1 Identification of the Substance/Mixture and of the Company/Undertaking Product Name: Genipin Company Name: Cayman Chemical Company 1180 E Ellsworth Rd Ann Arbor MI 48108

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Effect of Genipin on Cisplatin

Cisplatin (CSP) is a potent and widely used chemotherapeutic agent However clinical efficacy of CSP is compromised due to the elicitation of nephrotoxicity and ototoxicity In this study I have investigated the nephroprotective effects of a phytochemical – genipin (GP) isolated from gardenia flower (Gardenia jasminoides) on a murine model of cisplatin-induced nephropathy

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Hoechst 33342 Protocol for Imaging

Invitrogen Hoechst 33342 nucleic acid stain is a popular cell-permeant nuclear counterstain that emits blue fluorescence when bound to dsDNA This dye is often used to distinguish condensed pycnotic nuclei in apoptotic cells and for cell cycle studies in combination with BrdU

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Gelapin a degradable genipin cross

The synthesis of genipin cross-linked gelatin (Gelapin) hydrogel materials is presented Gelapin hydrogels were comprehensively characterised through chemical mechanical and physical analysis techniques It was found that the hydrogels could be cross-linked to up to 90% using a genipin concentration of 24 4% (w/ w) The hydrogels reach a stable swollen state and cease leaching of

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Product Name : Genipin

Product Name : Genipin Catalog Number : T2210 CAS Number : 6902-77-8 Molecular Formula : C11H14O5 Molecular Weight : 226 23 Structures : ANALYTICAL DATA HNMR Consistent with structure HPLC Shows 99 1% purity TA aDrrugg SceretenMing oExplert Certificate of Analysis techtargetmol | Tel: +1-857-239-0968 |

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Genipin

Genipin is a chemical compound found in Genipa americana fruit extract It is an aglycone derived from an iridoid glycoside called geniposide which is also present in fruit of Gardenia jasminoides Genipin is an excellent natural cross-linker for proteins collagen gelatin and chitosan cross-linking It has a low acute toxicity with LD 50 i v 382 mg/kg in mice therefore much less toxic

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Preparation of Genipin by Hydrolysis of Geniposide with

Co-immobilize enzyme by cross-linking and embedding optimize conditions for immobilizing determinate the enzymatic properties of co-immobilized enzyme and study the methods for preparation of genipin using co-immobilized enzyme to hydrolyze geniposide Optimized immobilizing conditions include glutaraldehyde concentration being 0 15% cross-linking temperature being 20C cross-linking time

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Genipin

genipin for defined durations (2 4 6 12 h) that matched the conditions from the rheology studies At the appropri-ate time point the genipin solution was removed and the gels were rinsed extensively with PBS Genipin-induced fluorescence was evaluated in two ways Some plates were transferred to the computer con- trolled stage of an Olympus IX81 inverted microscope (Olympus Melville NY

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Genipin

Genipin is a chemical compound found in gardenia fruit extract Genipin is an excellent natural cross-linker for proteins collagen gelatin and chitosan cross-linking Furthermore genipin can be used as a regulating agent for drug delivery as the raw material for gardenia blue pigment preparation and as the intermediate for alkaloid syntheses

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Antitumor Effects of Genipin: New and Emerging Insights

genipin focusing on antitumor effects and its mechanisms In brief genipin inhibits mitochondrial uncoupling protein 2 to increase accumulation of reactive oxygen species leading to ROS/c-Jun N-terminal kinase-dependent apoptosis of cancer cells

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Genipin Market Report

Global Genipin Market Insights Forecast to 2025 has complete details about market of Genipin industry Genipin analysis and current trends Global Genipin market size will increase to Million US$ by 2025 from Million US$ in 2018 at a CAGR of during the forecast period In this study 2018 has been considered as the base year and 2019 to 2025 as the forecast period to estimate the market

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Product Name : Genipin

Product Name : Genipin Catalog Number : T2210 CAS Number : 6902-77-8 Molecular Formula : C11H14O5 Molecular Weight : 226 23 Structures : ANALYTICAL DATA HNMR Consistent with structure HPLC Shows 99 1% purity TA aDrrugg SceretenMing oExplert Certificate of Analysis techtargetmol | Tel: +1-857-239-0968 |

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Global Genipin Market Insights Forecast to 2025

Global Genipin market size will increase to Million US$ by 2025 from Million US$ in 2017 at a CAGR of during the forecast period In this study 2017 has been considered as the base year and 2018 to 2025 as the forecast period to estimate the market size for Genipin

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Genipin 1

Product Name: genipin-1-b-D-gentiobioside Tel: +86-21-58589556 58589557 Email: saleszsuchem Chemieliva Pharmaceutical Co Ltd Product Name: genipin 1-gentiobioside Tel: 0086-23-67770219 Email: chemnetchemieliva View History Genipin 1-Gentiobioside Recently Updated 50--02-2 1975-9-2 205692-63-3 756-12-7 99728-16-2 7321-55-3 236117-38-7

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Gelapin a degradable genipin cross

The synthesis of genipin cross-linked gelatin (Gelapin) hydrogel materials is presented Gelapin hydrogels were comprehensively characterised through chemical mechanical and physical analysis techniques It was found that the hydrogels could be cross-linked to up to 90% using a genipin concentration of 24 4% (w/ w) The hydrogels reach a stable swollen state and cease leaching of

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genipin

Categories based on genipin: beta cgmp food gentiobioside grade IUPAC name CAS EINECS Formula (+)-Genipin 6902-77-8 C 1 1 H 1 4 O 5 Genipin food grade 6902-77-8 C 1 1 H 1 4 O 5 Genipin 1-gentiobioside 29307-60-6 C 2 3 H 3 4 O 1 5 Genipin cGMP and non-cGMP 6902-77-8 C 1 1 H 1 4 O 5 Genipin-1-b-D-gentiobioside Genipin 1-O-beta-D

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Tandem gene duplications drive divergent evolution of

ents are genipin and crocins were used as an imperial dye for royal costumes during the Qin and Han dynas-ties in China and are recorded in the Chinese Pharmacopoeia [8 9] Unlike coffee gardenia does not accumulate caffeine However in a pattern similar to

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Genipin ≥98% (HPLC) powder

Genipin is a natural cross linking agent which is extracted from gardenia fruit It prevents lipid peroxidation and production of nitric oxide Genipin protects the hippocampal neurons from the toxicity of Alzheimer′s amyloid β protein It has anti-inflammatory and anti-angiogenesis effects Genipin is involved in drug delivery system

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Genipin inhibits UCP2

Genipin inhibits UCP2-mediated proton leak and acutely reverses obesity- andhigh glucose-induced b celldysfunctionin isolated pancreatic islets Chen-Yu Zhang 1 2 5 * Laura E Parton 1 5 Chian Ping Ye 1 5 Stefan Krauss 1 4 Ruichao Shen 3 Cheng-Ting Lin 3 John A Porco Jr 3 and Bradford B Lowell1 *

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